A study in the Journal of Dentistry found that applying a preventive or therapeutic proximal microinvasive sealing of permanent teeth was associated with a reduced risk of caries in high-risk children, according to PracticeUpdate. The study included children ages 8 to 10 at baseline, who were evaluated after five years. "Application of a preventive interproximal sealant may prevent the future development of interproximal caries in the first permanent molars, especially in children at a high caries risk," according to Sompop Bencharit, D.D.S.

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